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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PDGFA Antibody (N-term) Blocking Peptide   

PDGFA Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P04085
Other Accession NP_002598
Clone Names 2082804
Peptide ID 2082804
Additional Information
Gene ID 5154
Other Names Platelet-derived growth factor subunit A, PDGF subunit A, PDGF-1, Platelet-derived growth factor A chain, Platelet-derived growth factor alpha polypeptide, PDGFA, PDGF1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1720a was selected from the N-term region of human PDGFA . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PDGF1
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity).
Cellular Location Secreted. Note=Released by platelets upon wounding
Research Areas
Citations (0)

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PDGFA is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth.


Monje, P., et al., Mol. Cell. Biol. 23(19):7030-7043 (2003).Gianni, D., et al., J. Biol. Chem. 278(11):9290-9297 (2003).Muller, C., et al., J. Biol. Chem. 278(20):18330-18335 (2003).Chui, C.M., et al., Cytokine 21(2):51-64 (2003).Laprise, M.H., et al., Blood 100(10):3578-3587 (2002).

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$ 80.00
Cat# BP1720a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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