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UBE2V2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q15819
Clone Names 100517313
Peptide ID 100517313
Additional Information
Gene ID 7336
Other Names Ubiquitin-conjugating enzyme E2 variant 2, DDVit 1, Enterocyte differentiation-associated factor 1, EDAF-1, Enterocyte differentiation-promoting factor 1, EDPF-1, MMS2 homolog, Vitamin D3-inducible protein, UBE2V2, MMS2, UEV2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE2V2
Synonyms MMS2, UEV2
Function Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Tissue Location Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues
Research Areas
Citations (0)

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Ubiquitin-conjugating enzyme E2 variant proteinsconstitute a distinct subfamily within the E2 protein family. Theyhave sequence similarity to other ubiquitin-conjugating enzymes butlack the conserved cysteine residue that is critical for thecatalytic activity of E2s. The protein encoded by this gene alsoshares homology with ubiquitin-conjugating enzyme E2 variant 1 andyeast MMS2 gene product. It may be involved in the differentiationof monocytes and enterocytes.


Wen, R., et al. Plant Cell 20(1):213-227(2008)Brun, J., et al. BMC Mol. Biol. 9, 24 (2008) :Pastushok, L., et al. FEBS Lett. 581(28):5343-5348(2007)Zhao, G.Y., et al. Mol. Cell 25(5):663-675(2007)Wen, R., et al. Plant Mol. Biol. 61 (1-2), 241-253 (2006) :

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$ 80.00
Cat# BP17212c
Availability: In Stock
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