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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TRAFD1 Antibody (C-term) Blocking Peptide   

TRAFD1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O14545
Clone Names 110617005
Peptide ID 110617005
Additional Information
Gene ID 10906
Other Names TRAF-type zinc finger domain-containing protein 1, Protein FLN29, TRAFD1, FLN29
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FLN29
Function Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
Research Areas
Citations (0)

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The innate immune system confers host defense againstviral and microbial infection, and TRAFD1 is a negative feedbackregulator that controls excessive immune responses (Sanada et al.,2008 [PubMed 18849341]).


Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)Sanada, T., et al. J. Biol. Chem. 283(49):33858-33864(2008)Nature 447(7145):661-678(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)

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$ 80.00
Cat# BP17218b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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