|Other Names||Ubiquitin-conjugating enzyme E2 Z, Uba6-specific E2 conjugating enzyme 1, Use1, Ubiquitin carrier protein Z, Ubiquitin-protein ligase Z, UBE2Z|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Widely expressed. Highly in placenta, pancreas, spleen and testis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Modification of proteins with ubiquitin (UBB; MIM 191339)or ubiquitin-like proteins controls many signaling networks andrequires a ubiquitin activating enzyme (E1), a ubiquitinconjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Zis an E2 enzyme (Jin et al., 2007 [PubMed 17597759]).[supplied byOMIM].
Gu, X., et al. Mol. Biol. Rep. 34(3):183-188(2007)Jin, J., et al. Nature 447(7148):1135-1138(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.