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TH1L Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IXH7
Clone Names 100623261
Peptide ID 100623261
Additional Information
Gene ID 51497
Other Names Negative elongation factor C/D, NELF-C/D, TH1-like protein, NELFCD, NELFD, TH1, TH1L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms NELFD, TH1, TH1L
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
Cellular Location Nucleus.
Tissue Location Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal and cardiac muscle, adrenal, thyroid, kidney and pancreas.
Research Areas
Citations (0)

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The NELF complex of proteins interacts with the DSIFprotein complex to repress transcriptional elongation by RNApolymerase II. The protein encoded by this gene is an essentialpart of the NELF complex. Alternative translation initiation siteusage results in the formation of two isoforms with differentN-termini.


Zou, W., et al. Cancer Sci. 101(10):2156-2162(2010)Yang, Y., et al. J. Cell. Biochem. 109(5):1013-1024(2010)Sun, J., et al. J. Biol. Chem. 285(9):6443-6452(2010)Pal, P., et al. Croat. Med. J. 50(4):361-369(2009)Cheng, C., et al. J. Biol. Chem. 284(13):8786-8796(2009)

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$ 80.00
Cat# BP17236b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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