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BIKE Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NSY1
Clone Names 2090702
Additional Information
Gene ID 55589
Other Names BMP-2-inducible protein kinase, BIKe, BMP2K, BIKE
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1723a was selected from the Center region of human BIKE . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP2K
Synonyms BIKE
Function May be involved in osteoblast differentiation.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

BIKE is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation.

References

Kearns, A.E., et al., J. Biol. Chem. 276(45):42213-42218 (2001).Hoffmann, A., et al., Crit. Rev. Eukaryot. Gene Expr. 11 (1-3), 23-45 (2001).

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$ 277.78
Cat# BP1723a
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