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GRIK5 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q16478
Clone Names 100712162
Additional Information
Gene ID 2901
Other Names Glutamate receptor ionotropic, kainate 5, GluK5, Excitatory amino acid receptor 2, EAA2, Glutamate receptor KA-2, KA2, GRIK5, GRIK2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRIK5
Synonyms GRIK2
Function Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R- ACPD.
Cellular Location Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein that belongs to theglutamate-gated ionic channel family. Glutamate functions as themajor excitatory neurotransmitter in the central nervous systemthrough activation of ligand-gated ion channels and Gprotein-coupled membrane receptors. The protein encoded by thisgene forms functional heteromeric kainate-preferring ionic channelswith the subunits encoded by related gene family members. [providedby RefSeq].

References

Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Gill, M.B., et al. J. Biol. Chem. 284(21):14503-14512(2009)Arai, S., et al. Psychiatr. Genet. 19(1):6-13(2009)Fotheringham, J., et al. J Neuroimmune Pharmacol 3(2):105-116(2008)Shibata, H., et al. Psychiatry Res 141(1):39-51(2006)

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$ 277.78
Cat# BP17247a
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