Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   ESX1 Antibody (N-term) Blocking Peptide   

ESX1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8N693
Clone Names 110726053
Peptide ID 110726053
Additional Information
Gene ID 80712
Other Names Homeobox protein ESX1, Extraembryonic, spermatogenesis, homeobox 1, Homeobox protein ESX1-N, Homeobox protein ESX1-C, ESX1, ESX1L, ESX1R
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ESX1
Synonyms ESX1L, ESX1R
Function May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover.
Cellular Location Cytoplasm. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:15235584}. Note=ESXR1-N localizes specifically to the nucleus while ESXR1-C localizes specifically to the cytoplasm
Tissue Location Expressed in placenta and testis. Expressed in testicular germ cell tumors.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


This gene encodes a dual-function 65 kDa protein thatundergoes proteolytic cleavage to produce a 45 kDa N-terminalfragment with a paired-like homeodomain and a 20 kDa C-terminalfragment with a proline-rich domain. The C-terminal fragmentlocalizes to the cytoplasm while the N-terminal fragment localizesexclusively to the nucleus. In contrast to human, the mouse homologhas a novel PN/PF motif in the C-terminus and is paternallyimprinted in placental tissue. This gene likely plays a role inplacental development and spermatogenesis.


Bonaparte, E., et al. Hum. Reprod. 25(6):1398-1403(2010)Wang, X., et al. Hum. Mol. Genet. 16(17):2053-2060(2007)Loschiavo, M., et al. Mamm. Genome 18(1):75-85(2007)Murthi, P., et al. Mol. Hum. Reprod. 12(5):335-340(2006)Yanagihara, M., et al. Oncogene 24(38):5878-5887(2005)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP17259a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions