|Other Names||Malonyl-CoA-acyl carrier protein transacylase, mitochondrial, MCT, Mitochondrial malonyl CoA:ACP acyltransferase, Mitochondrial malonyltransferase, [Acyl-carrier-protein] malonyltransferase, MCAT, MT|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is found exclusively inthe mitochondrion, where it catalyzes the transfer of a malonylgroup from malonyl-CoA to the mitochondrial acyl carrier protein.The encoded protein may be part of a fatty acid synthase complexthat is more like the type II prokaryotic and plastid complexesrather than the type I human cytosolic complex. Two transcriptvariants encoding different isoforms have been found for this gene.
Kim, S.T., et al. Prostate 70(16):1729-1738(2010)Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)Ma, J., et al. Atherosclerosis 191(1):63-72(2007)Kuhl, J.E., et al. Am. J. Physiol. Endocrinol. Metab. 290 (6), E1296-E1303 (2006) :Zhang, L., et al. J. Biol. Chem. 278(41):40067-40074(2003)
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