|Other Names||Ankyrin repeat and BTB/POZ domain-containing protein 1, Elongation factor 1A-binding protein, ABTB1 (HGNC:18275)|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.|
|Tissue Location||Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart|
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This gene encodes a protein with an ankyrin repeat regionand two BTB/POZ domains, which are thought to be involved inprotein-protein interactions. Expression of this gene is activatedby the phosphatase and tensin homolog, a tumor suppressor.Alternate splicing results in three transcript variants. [providedby RefSeq].
Koiwai, K., et al. Genes Cells 13(6):593-607(2008)Maezawa, S., et al. Genes Cells 13(5):439-457(2008)Unoki, M., et al. Oncogene 20(33):4457-4465(2001)Dai, K.S., et al. Biochem. Biophys. Res. Commun. 273(3):991-996(2000)
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