CNTNAP4 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9C0A0 |
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Clone Names | 110717031 |
Gene ID | 85445 |
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Other Names | Contactin-associated protein-like 4, Cell recognition molecule Caspr4, CNTNAP4, CASPR4, KIAA1763 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CNTNAP4 |
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Synonyms | CASPR4, KIAA1763 |
Function | Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system (By similarity). |
Cellular Location | Presynaptic cell membrane {ECO:0000250|UniProtKB:Q99P47}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q99P47}. Note=Specifically present within the presynaptic compartment of synapses. {ECO:0000250|UniProtKB:Q99P47} |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene product belongs to the neurexin family, membersof which function in the vertebrate nervous system as cell adhesionmolecules and receptors. This protein, like other neurexinproteins, contains epidermal growth factor repeats and laminin Gdomains. In addition, it includes an F5/8 type C domain,discoidin/neuropilin- and fibrinogen-like domains, andthrombospondin N-terminal-like domains. Alternative splicingresults in two transcript variants encoding different isoforms.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)Lasky-Su, J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1345-1354 (2008) :Nordgard, S.H., et al. Genes Chromosomes Cancer 47(8):680-696(2008)Kim, J.M., et al. DNA Res. 13(6):275-286(2006)
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