|Other Names||Transcription factor 25, TCF-25, Nuclear localized protein 1, TCF25, KIAA1049, NULP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.|
|Cellular Location||Nucleus. Note=Some staining in the cytosol|
|Tissue Location||In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.|
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Provided below are standard protocols that you may find useful for product applications.
TCF25 is a member of the basic helix-loop-helix (bHLH)family of transcription factors that are important in embryonicdevelopment (Steen and Lindholm, 2008 [PubMed 18068114]).[suppliedby OMIM].
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Steen, H., et al. Biochem. Biophys. Res. Commun. 366(2):432-437(2008)Cai, Z., et al. Biochem. Biophys. Res. Commun. 343(3):973-981(2006)
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