|Other Names||Putative E3 ubiquitin-protein ligase UNKL, 632-, RING finger protein unkempt-like, Zinc finger CCCH domain-containing protein 5-like, UNKL, C16orf28, ZC3H5L, ZC3HDC5L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C16orf28, ZC3H5L, ZC3HDC5L|
|Function||May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven.|
|Cellular Location||Isoform 4: Cytoplasm. Nucleus. Note=Isoform 4 is primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm|
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UNKL may participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven.
Lores, P., et al. FEBS J. 277(6):1453-1464(2010)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)Martin, J., et al. Nature 432(7020):988-994(2004)Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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