UNKL Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H9P5 |
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Clone Names | 110617233 |
Gene ID | 64718 |
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Other Names | Putative E3 ubiquitin-protein ligase UNKL, 632-, RING finger protein unkempt-like, Zinc finger CCCH domain-containing protein 5-like, UNKL, C16orf28, ZC3H5L, ZC3HDC5L |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | UNKL |
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Synonyms | C16orf28, ZC3H5L, ZC3HDC5L |
Function | May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven. |
Cellular Location | [Isoform 4]: Cytoplasm. Nucleus. Note=Isoform 4 is primarily localized in the cytoplasm but has the ability to shuttle between the nucleus and the cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
UNKL may participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven.
References
Lores, P., et al. FEBS J. 277(6):1453-1464(2010)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)Martin, J., et al. Nature 432(7020):988-994(2004)Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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