|Other Names||SRSF protein kinase 3, Muscle-specific serine kinase 1, MSSK-1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine/threonine-protein kinase 23, Srpk3, Mssk1, Stk23|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.|
|Tissue Location||Exclusively expressed in skeletal and heart muscle.|
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Provided below are standard protocols that you may find useful for product applications.
Srpk3 is required for normal muscle development.
Potthoff, M.J., et al. Mol. Cell. Biol. 27(23):8143-8151(2007)Davie, J.K., et al. Dev. Biol. 311(2):650-664(2007)Nakagawa, O., et al. Genes Dev. 19(17):2066-2077(2005)
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