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Mouse Tlk1 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession Q8C0V0
Clone Names 110328128
Peptide ID 110328128
Additional Information
Gene ID 228012
Other Names Serine/threonine-protein kinase tousled-like 1, Tousled-like kinase 1, Tlk1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tlk1
Function Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed in all tissues examined.
Research Areas
Citations (0)

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Background

Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).

References

Canfield, C., et al. BMC Mol. Biol. 10, 110 (2009) :Taniwaki, T., et al. Dev. Growth Differ. 47(3):163-172(2005)Sunavala-Dossabhoy, G., et al. BMC Mol. Biol. 6, 19 (2005) :Cobellis, G., et al. Nucleic Acids Res. 33 (4), E44 (2005) :Okazaki, N., et al. DNA Res. 11(3):205-218(2004)

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$ 80.00
Cat# BP17323b
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