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AOAH Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P28039
Clone Names 110617045
Peptide ID 110617045
Additional Information
Gene ID 313
Other Names Acyloxyacyl hydrolase, Acyloxyacyl hydrolase small subunit, Acyloxyacyl hydrolase large subunit, AOAH
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AOAH
Function Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

This locus encodes both the light and heavy subunits ofacyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysisof acyloxylacyl-linked fatty acyl chains from bacteriallipopolysaccharides, effectively detoxifying these molecules. Theencoded protein may play a role in modulating host inflammatoryresponse to gram-negative bacteria. Alternatively splicedtranscript variants have been described.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Pelak, K., et al. J. Infect. Dis. 201(8):1141-1149(2010)Barnes, K.C., et al. J. Allergy Clin. Immunol. 118(1):70-77(2006)Coulthard, M.G., et al. Infect. Immun. 64(5):1510-1515(1996)Staab, J.F., et al. J. Biol. Chem. 269(38):23736-23742(1994)

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$ 80.00
Cat# BP17325c
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