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SOX7 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BT81
Clone Names 110617200
Peptide ID 110617200
Additional Information
Gene ID 83595
Other Names Transcription factor SOX-7, SOX7
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX7
Function Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}. Cytoplasm
Tissue Location Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation.
Research Areas
Citations (0)

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This gene encodes a member of the SOX (SRY-relatedHMG-box) family of transcription factors involved in the regulationof embryonic development and in the determination of the cell fate.The encoded protein may act as a transcriptional regulator afterforming a protein complex with other proteins. The protein may playa role in tumorigenesis. A similar protein in mice is involved inthe regulation of the wingless-type MMTV integration site family(Wnt) pathway.


Zhang, Y., et al. Cancer Lett. 277(1):29-37(2009)Semb, H. Cell Stem Cell 3(4):355-356(2008)Guo, L., et al. Mol. Cancer Res. 6(9):1421-1430(2008)Seguin, C.A., et al. Cell Stem Cell 3(2):182-195(2008)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)

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$ 80.00
Cat# BP17335b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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