|Other Names||Peflin, PEF protein with a long N-terminal hydrophobic domain, Penta-EF hand domain-containing protein 1, PEF1, ABP32|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated in the presence of Ca(2+)|
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This gene encodes a calcium-binding protein belonging tothe penta-EF-hand protein family. The encoded protein has beenshown to form a heterodimer with the programmed cell death 6 geneproduct and may modulate its function in Ca(2+) signaling.Alternative splicing results in multiple transcript variants and apseudogene has been identified on chromosome 1.
Lamesch, P., et al. Genomics 89(3):307-315(2007)Hansen, C., et al. FEBS Lett. 545 (2-3), 151-154 (2003) :Satoh, H., et al. Biochim. Biophys. Acta 1600 (1-2), 61-67 (2002) :Kitaura, Y., et al. Arch. Biochem. Biophys. 399(1):12-18(2002)Kitaura, Y., et al. J. Biol. Chem. 276(17):14053-14058(2001)
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