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LAS1L Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9Y4W2
Clone Names 110617286
Peptide ID 110617286
Additional Information
Gene ID 81887
Other Names Ribosomal biogenesis protein LAS1L, Protein LAS1 homolog, LAS1L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LAS1L
Function Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Cellular Location Nucleus, nucleolus Nucleus, nucleoplasm. Cytoplasm Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export
Research Areas
Citations (0)

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The function of LAS1L has not been determined.


Castle, C.D., et al. Mol. Cell. Biol. 30(18):4404-4414(2010)Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)

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$ 80.00
Cat# BP17345b
(40 western blots)
Availability: In Stock
Bulk Size
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