|Other Names||One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the onecut family oftranscription factors, which are characterized by a cut domain andan atypical homeodomain. The protein binds to specific DNAsequences and stimulates expression of target genes, includinggenes involved in melanocyte and hepatocyte differentiation.
Furuno, K., et al. Genes Immun. 9(4):302-308(2008)Pike, B.L., et al. Leukemia 22(5):1035-1043(2008)Rauch, T., et al. Cancer Res. 66(16):7939-7947(2006)Jacquemin, P., et al. Biochem. Biophys. Res. Commun. 285(5):1200-1205(2001)Jacquemin, P., et al. J. Biol. Chem. 274(5):2665-2671(1999)
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