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HMGN5 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P82970 |
|---|---|
| Clone Names | 110729102 |
| Gene ID | 79366 |
|---|---|
| Other Names | High mobility group nucleosome-binding domain-containing protein 5, Nucleosome-binding protein 1, HMGN5, NSBP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | HMGN5 |
|---|---|
| Synonyms | NSBP1 |
| Function | Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. |
| Cellular Location | Nucleus. Note=Associates with nucleosomes in euchromatin and is largely excluded from constitutive heterochromatin. |
| Tissue Location | Ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a nuclear protein with similarities tothe high mobility group proteins, HMG14 and HMG17, which suggeststhat this protein may function as a nucleosomal binding andtranscriptional activating protein.
References
Rochman, M., et al. Biochim. Biophys. Acta 1799 (1-2), 86-92 (2010) :Rochman, M., et al. Mol. Cell 35(5):642-656(2009)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)King, L.M., et al. Genomics 71(2):163-173(2001)
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