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TMTC3 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6ZXV5
Clone Names 91119101
Additional Information
Gene ID 160418
Other Names Transmembrane and TPR repeat-containing protein 3, Protein SMILE, TMTC3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMTC3 (HGNC:26899)
Function Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3 (PubMed:28973932). Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response.
Cellular Location Membrane; Multi-pass membrane protein. Endoplasmic reticulum. Note=In odontoblast cultures, it colocalizes with PDIA3 in the endoplasmic reticulum
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein that belongs to thetransmembrane and tetratricopeptide repeat-containing proteinfamily.

References

Mehrle, A., et al. Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006) :

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$ 277.78
Cat# BP17381b
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