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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NET1 Antibody (Center) Blocking Peptide   

NET1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7Z628
Clone Names 100528101
Peptide ID 100528101
Additional Information
Gene ID 10276
Other Names Neuroepithelial cell-transforming gene 1 protein, Proto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8, NET1, ARHGEF8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NET1
Synonyms ARHGEF8
Function Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Cellular Location Cytoplasm. Nucleus
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Background

NET1 acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway (By similarity).

References

Lee, J., et al. J. Biol. Chem. 285(34):26618-26627(2010)Carr, H.S., et al. J. Biol. Chem. 284(36):24269-24280(2009)Gilcrease, M.Z., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):80-86(2009)Murray, D., et al. Br. J. Cancer 99(8):1322-1329(2008)Guerra, L., et al. PLoS ONE 3 (5), E2254 (2008) :

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$ 80.00
Cat# BP17382c
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