|Other Names||E3 ubiquitin-protein ligase TRIM41, 632-, RING finger-interacting protein with C kinase, RINCK, Tripartite motif-containing protein 41, TRIM41, RINCK|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Functions as an E3 ligase that catalyzes the ubiquitin- mediated degradation of protein kinase C.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Expressed in multiple tissues with the highest levels in heart and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
TRIM41 belongs to a family of tripartite motif (TRIM)proteins defined as containing a RING finger, one or more B-boxdomains, and a coiled-coil region (Tanaka et al., 2005 [PubMed16022281]). See TRIM45 (MIM 609318).
Chen, D., et al. J. Biol. Chem. 282(46):33776-33787(2007)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)Tanaka, M., et al. Mol. Biol. Rep. 32(2):87-93(2005)Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
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