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GPR84 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NQS5
Clone Names 100617005
Peptide ID 100617005
Additional Information
Gene ID 53831
Other Names G-protein coupled receptor 84, Inflammation-related G-protein coupled receptor EX33, GPR84, EX33
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPR84
Synonyms EX33
Function Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within the leukocyte population expression is higher in neutrophils and eosinophils relative to T- or B-lymphocytes
Research Areas
Citations (0)

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Background

Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.

References

Takeda, S., et al. FEBS Lett. 520 (1-3), 97-101 (2002) :Yousefi, S., et al. J. Leukoc. Biol. 69(6):1045-1052(2001)Wittenberger, T., et al. J. Mol. Biol. 307(3):799-813(2001)

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$ 80.00
Cat# BP17390c
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