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PAFAH2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99487
Clone Names 110617190
Peptide ID 110617190
Additional Information
Gene ID 5051
Other Names Platelet-activating factor acetylhydrolase 2, cytoplasmic, Serine-dependent phospholipase A2, SD-PLA2, hSD-PLA2, PAFAH2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.
Cellular Location Cytoplasm. Membrane {ECO:0000250|UniProtKB:P79106}; Lipid-anchor {ECO:0000250|UniProtKB:P79106}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P79106}; Lipid-anchor {ECO:0000250|UniProtKB:P79106}. Note=In resting cells, localizes to intracellular membranes and cytoplasm. Translocates from the cytoplasm to intracellular membranes upon oxidative stress {ECO:0000250|UniProtKB:P79106}
Tissue Location Broadly expressed in different tissues, but high in B- and T-lymphocytes. In brain, expression is restricted to amygdala and frontal cortex.
Research Areas
Citations (0)

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This gene encodes platelet-activating factoracetylhydrolase isoform 2, a single-subunit intracellular enzymethat catalyzes the removal of the acetyl group at the SN-2 positionof platelet-activating factor (identified as1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, thislipase exhibits a broader substrate specificity than simplyplatelet activating factor. Two other isoforms of intracellularplatelet-activating factor acetylhydrolase exist, and both aremulti-subunit enzymes. Additionally, there is a single-subunitserum isoform of this enzyme.


Schmidt, E.B., et al. Atherosclerosis 196(1):420-424(2008)Umemura, K., et al. Stroke 38(3):1063-1068(2007)Unno, N., et al. J. Surg. Res. 134(1):36-43(2006)Marques, M., et al. J. Invest. Dermatol. 119(4):913-919(2002)Min, J.H., et al. Biochemistry 40(15):4539-4549(2001)

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$ 80.00
Cat# BP17398c
Availability: In Stock
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