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SRA1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9HD15
Clone Names 100430122
Peptide ID 100430122
Additional Information
Gene ID 10011
Other Names Steroid receptor RNA activator 1, Steroid receptor RNA activator protein, SRAP, SRA1 (HGNC:11281)
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRA1 (HGNC:11281)
Function Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
Cellular Location Nucleus. Cytoplasm
Tissue Location Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up- regulated in human tumors of the breast, ovary, and uterus
Research Areas
Citations (0)

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This gene is involved in transcriptional coactivation bysteroid receptors. There is currently data suggesting this geneencodes both a non-coding RNA that functions as part of aribonucleoprotein complex and a protein coding mRNA. Increasedexpression of both the transcript and the protein is associatedwith cancer.


Yao, H., et al. Genes Dev. 24(22):2543-2555(2010)Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Beauvillain, C., et al. J. Hepatol. 52(5):644-651(2010)Foulds, C.E., et al. Mol. Endocrinol. 24(5):1090-1105(2010)Chooniedass-Kothari, S., et al. FEBS Lett. 584(6):1174-1180(2010)

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$ 80.00
Cat# BP17404b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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