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NKX2-5 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P52952
Clone Names 100507231
Peptide ID 100507231
Additional Information
Gene ID 1482
Other Names Homeobox protein Nkx-25, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E, NKX2-5, CSX, NKX25, NKX2E
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX2-5
Synonyms CSX, NKX2.5, NKX2E
Function Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.
Cellular Location Nucleus.
Tissue Location Expressed only in the heart.
Research Areas
Citations (0)

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This gene encodes a homeobox-containing transcriptionfactor. This transcription factor functions in heart formation anddevelopment. Mutations in this gene cause atrial septal defect withatrioventricular conduction defect, and also tetralogy of Fallot,which are both heart malformation diseases. Mutations in this genecan also cause congenital hypothyroidism non-goitrous type 5, anon-autoimmune condition. Alternative splicing results in multipletranscript variants.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)De Luca, A., et al. Clin. Genet. (2010) In press :Stallmeyer, B., et al. Clin. Genet. (2010) In press :Narumi, S., et al. J. Clin. Endocrinol. Metab. 95(4):1981-1985(2010)Joubert, B.R., et al. Genome Med 2 (3), 17 (2010) :

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$ 80.00
Cat# BP17406c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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