|Other Names||Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressor, PDGFRL, PRLTS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in colon, lung and liver.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein with significant sequencesimilarity to the ligand binding domain of platelet-derived growthfactor receptor beta. Mutations in this gene, or deletion of achromosomal segment containing this gene, are associated withsporadic hepatocellular carcinomas, colorectal cancers, andnon-small cell lung cancers. This suggests this gene product mayfunction as a tumor suppressor.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Guo, F.J., et al. World J. Gastroenterol. 16(12):1465-1472(2010)Riker, A.I., et al. BMC Med Genomics 1, 13 (2008) :Xu, M., et al. BMC Genomics 9 SUPPL 1, S12 (2008) :Seitz, S., et al. Genes Chromosomes Cancer 45(6):612-627(2006)
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