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PDGFRL Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15198
Clone Names 100617219
Additional Information
Gene ID 5157
Other Names Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressor, PDGFRL, PRLTS
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDGFRL
Synonyms PRLTS
Cellular Location Secreted.
Tissue Location Expressed in colon, lung and liver.
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein with significant sequencesimilarity to the ligand binding domain of platelet-derived growthfactor receptor beta. Mutations in this gene, or deletion of achromosomal segment containing this gene, are associated withsporadic hepatocellular carcinomas, colorectal cancers, andnon-small cell lung cancers. This suggests this gene product mayfunction as a tumor suppressor.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)Guo, F.J., et al. World J. Gastroenterol. 16(12):1465-1472(2010)Riker, A.I., et al. BMC Med Genomics 1, 13 (2008) :Xu, M., et al. BMC Genomics 9 SUPPL 1, S12 (2008) :Seitz, S., et al. Genes Chromosomes Cancer 45(6):612-627(2006)

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$ 277.78
Cat# BP17414a
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