|Other Names||Hepatic leukemia factor, HLF|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Highly expressed in liver; lower levels in lung and kidney|
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This gene encodes a member of the proline and acidic-rich(PAR) protein family, a subset of the bZIP transcription factors.The encoded protein forms homodimers or heterodimers with other PARfamily members and binds sequence-specific promoter elements toactivate transcription. Chromosomal translocations fusing portionsof this gene with the E2A gene cause a subset of childhoodB-lineage acute lymphoid leukemias. Alternatively splicedtranscript variants have been described, but their biologicalvalidity has not been determined.
Hirose, K., et al. Blood 116(6):962-970(2010)Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Otto, T., et al. Endocrinology 149(5):2241-2250(2008)Inukai, T., et al. Leukemia 21(2):288-296(2007)He, J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22(5):551-553(2005)
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