|Other Names||Actin-binding LIM protein 3, abLIM-3, Actin-binding LIM protein family member 3, ABLIM3, KIAA0843|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.|
|Tissue Location||Expressed predominantly in heart and brain.|
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Provided below are standard protocols that you may find useful for product applications.
The LIM domain is a double zinc finger structure thatpromotes protein-protein interactions. LIM domain proteins, such asABLIM3, play roles in embryonic development, cell lineagedetermination, and cancer (Krupp et al., 2006 [PubMed16328021]).
Barrientos, T., et al. J. Biol. Chem. 282(11):8393-8403(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Krupp, M., et al. Int. J. Mol. Med. 17(1):129-133(2006)Zheng, B., et al. Biochim. Biophys. Acta 1690(1):1-10(2004)Yamada, S., et al. Oncogene 23(35):5901-5911(2004)
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