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METTL13 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8N6R0
Clone Names 110617145
Additional Information
Gene ID 51603
Other Names Methyltransferase-like protein 13, 211-, METTL13, KIAA0859
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name METTL13 (HGNC:24248)
Function Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation (PubMed:30612740, PubMed:30143613). Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2' (PubMed:30143613). Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55' (PubMed:30612740, PubMed:30143613). Has no activity towards core histones H2A, H2B, H3 and H4 (PubMed:30612740). Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6 (PubMed:26763933).
Cellular Location Cytoplasm. Nucleus. Mitochondrion
Research Areas
Citations (0)
citation

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Background

The function of this protein remains unknown.

References

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)

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$ 277.78
Cat# BP17454c
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Availability: 2 weeks
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