|Other Names||Serologically defined colon cancer antigen 8, Antigen NY-CO-8, Centrosomal colon cancer autoantigen protein, hCCCAP, SDCCAG8, CCCAP, NPHP10|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell junction Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle|
|Tissue Location||Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a centrosome associated protein. Thisprotein may be involved in organizing the centrosome duringinterphase and mitosis. Mutations in this gene are associated withretinal-renal ciliopathy.
Otto, E.A., et al. Nat. Genet. 42(10):840-850(2010)Scherag, A., et al. PLoS Genet. 6 (4), E1000916 (2010) :McCauley, J.L., et al. Genes Immun. 10(7):624-630(2009)Kenedy, A.A., et al. Gene 303, 35-46 (2003) :Scanlan, M.J., et al. Int. J. Cancer 76(5):652-658(1998)
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