|Other Names||Oxysterol-binding protein-related protein 6, ORP-6, OSBP-related protein 6, OSBPL6, ORP6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Weakly binds 25-hydroxycholesterol.|
|Cellular Location||Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope Cell membrane; Peripheral membrane protein|
|Tissue Location||Expressed in brain and striated muscle (at protein level) (PubMed:14593528). Widely expressed (PubMed:11735225). Expressed in skeletal muscle (PubMed:14593528)|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the oxysterol-bindingprotein (OSBP) family, a group of intracellular lipid receptors.Most members contain an N-terminal pleckstrin homology domain and ahighly conserved C-terminal OSBP-like sterol-binding domain.Transcript variants encoding different isoforms have beenidentified.
Maestrini, E., et al. Mol. Psychiatry 15(9):954-968(2010)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Lehto, M., et al. Cell Tissue Res. 315(1):39-57(2004)Jaworski, C.J., et al. Genomics 78(3):185-196(2001)Lehto, M., et al. J. Lipid Res. 42(8):1203-1213(2001)
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