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FAM189A2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15884 |
|---|---|
| Clone Names | 110729082 |
| Gene ID | 9413 |
|---|---|
| Other Names | Protein FAM189A2, Protein X123, FAM189A2, C9orf61, X123 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ENTREP1 (HGNC:24820) |
|---|---|
| Function | Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway. |
| Cellular Location | Early endosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Recycling endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Enriched in endosomes compared to the cell membrane. |
| Tissue Location | Prominently expressed in muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Humphray, S.J., et al. Nature 429(6990):369-374(2004)Duclos, F., et al. Hum. Mol. Genet. 3(6):909-914(1994)
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