|Other Names||F-box/WD repeat-containing protein 9, F-box and WD-40 domain-containing protein 9, FBXW9, FBW9|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.|
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Provided below are standard protocols that you may find useful for product applications.
Members of the F-box protein family, such as FBXW9, arecharacterized by an approximately 40-amino acid F-box motif. SCFcomplexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM603034), and F-box proteins, act as protein-ubiquitin ligases.F-box proteins interact with SKP1 through the F box, and theyinteract with ubiquitination targets through other proteininteraction domains (Jin et al., 2004 [PubMed 15520277]).[suppliedby OMIM].
Lievens, S., et al. J. Proteome Res. 8(2):877-886(2009)Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
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