|Other Names||Secretogranin-3, Secretogranin III, SgIII, SCG3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein Secreted. Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts in intragranular conditions (By similarity). Neuroendocrine and endocrine secretory granules.|
|Tissue Location||Expressed in brain, heart, kidney, liver and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of thechromogranin/secretogranin family of neuroendocrine secretoryproteins. Granins may serve as precursors for biologically activepeptides. Some granins have been shown to function as helperproteins in sorting and proteolytic processing of prohormones;however, the function of this protein is unknown. Two transcriptvariants encoding different isoforms have been found for this gene.
Li, X., et al. J. Allergy Clin. Immunol. 125(2):328-335(2010)He, C., et al. Clin. Chim. Acta 402 (1-2), 102-106 (2009) :Stridsberg, M., et al. Regul. Pept. 148 (1-3), 95-98 (2008) :Tanabe, A., et al. J. Clin. Endocrinol. Metab. 92(3):1145-1154(2007)Sakai, Y., et al. Arch. Histol. Cytol. 67(1):57-64(2004)
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