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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NOXO1 Antibody (Center) Blocking Peptide   

NOXO1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NFA2
Clone Names 100712320
Peptide ID 100712320
Additional Information
Gene ID 124056
Other Names NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX, SH3PXD5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOXO1
Synonyms P41NOX, SH3PXD5
Function Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.
Cellular Location Isoform 3: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Isoform 3 associates with the plasma membrane in a lipid-dependent manner (PubMed:12716910)
Tissue Location Expressed in testis, small and large intestines, liver, kidney and pancreas. Isoform 3 is mainly expressed in colon. Isoform 1 is preferentially expressed in testis.
Research Areas
Citations (0)

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NADPH oxidases (NOXs) catalyze the transfer of electronsfrom NADPH to molecular oxygen to generate reactive oxygen species(ROS). NOX organizers, such as NOXO1, target NOX activators (seeNOXA1; MIM 611255) to NOX and also target NOX to differentsubcellular compartments (Opitz et al., 2007 [PubMed17189823]).


Dutta, S., et al. PLoS ONE 5 (5), E10478 (2010) :Opitz, N., et al. Free Radic. Biol. Med. 42(2):175-179(2007)Yamamoto, A., et al. Biochem. Biophys. Res. Commun. 352(2):560-565(2007)Takeya, R., et al. FEBS J. 273(16):3663-3677(2006)Cheng, G., et al. J. Biol. Chem. 281(26):17718-17726(2006)

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$ 80.00
Cat# BP17494c
Availability: In Stock
Bulk Size
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