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BATF2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N1L9 |
|---|---|
| Clone Names | 110808077 |
| Gene ID | 116071 |
|---|---|
| Other Names | Basic leucine zipper transcriptional factor ATF-like 2, B-ATF-2, Suppressor of AP-1 regulated by IFN, SARI, BATF2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BATF2 |
|---|---|
| Function | AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CCN1 promoter. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
MGC20410 belongs to the bZIP family. It contains one bZIP domain. There are two isoforms.
References
Dash, R., et al. Oncogene 29(31):4412-4423(2010)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Su, Z.Z., et al. Proc. Natl. Acad. Sci. U.S.A. 105(52):20906-20911(2008)Lim, J., et al. Cell 125(4):801-814(2006)
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