CDC20B Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q86Y33 |
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Clone Names | 110808099 |
Gene ID | 166979 |
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Other Names | Cell division cycle protein 20 homolog B, CDC20B |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CDC20B (HGNC:24222) |
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Function | Protein regulator of centriole-deuterosome disengagement and subsequently participates in the ciliogenesis in multiciliated cells (MCCs). |
Cellular Location | Cytoplasm. Note=Tightly associated to mature deuterosomes. |
Tissue Location | Expressed in multiciliated cells (MCCs). |
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Provided below are standard protocols that you may find useful for product applications.
Background
The timely destruction of key regulators through ubiquitin-mediated proteolysis ensures the orderly progression of the cell cycle. The APC (anaphase-promoting complex) is a major component of this degradation machinery and its activation is required for the execution of critical events. CDC20B has been implicated as a meiosis specific activator of APC and is required for sporulation in budding yeast.
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)Ota, T., et al. Nat. Genet. 36(1):40-45(2004)Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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