|Other Names||DNA damage-inducible transcript 4-like protein, HIF-1 responsive protein RTP801-like, Protein regulated in development and DNA damage response 2, REDD-2, DDIT4L, REDD2, RTP801L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.|
|Tissue Location||Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery|
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Provided below are standard protocols that you may find useful for product applications.
DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Koga, Y., et al. Genome Res. 19(8):1462-1470(2009)Imen, J.S., et al. Free Radic. Biol. Med. 46(10):1404-1410(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Corradetti, M.N., et al. J. Biol. Chem. 280(11):9769-9772(2005)Cuaz-Perolin, C., et al. Arterioscler. Thromb. Vasc. Biol. 24(10):1830-1835(2004)
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