ERP27 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96DN0 |
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Clone Names | 110808132 |
Gene ID | 121506 |
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Other Names | Endoplasmic reticulum resident protein 27, ER protein 27, ERp27, ERP27, C12orf46 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ERP27 |
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Synonyms | C12orf46 |
Function | Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates (PubMed:16940051, PubMed:23192347). Binds protein substrates via a hydrophobic pocket in the C-terminal domain (PubMed:16940051, PubMed:23192347). May play a role in the unfolded stress response (PubMed:23192347). |
Cellular Location | Endoplasmic reticulum lumen |
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Provided below are standard protocols that you may find useful for product applications.
Background
ERP27 is a noncatalytic member of the protein disulfideisomerase (PDI; see MIM 608012) family of endoplasmic reticulum(ER) proteins (Alanen et al., 2006 [PubMed 16940051]).[supplied byOMIM].
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)Alanen, H.I., et al. J. Biol. Chem. 281(44):33727-33738(2006)Lim, J., et al. Cell 125(4):801-814(2006)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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