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TGM3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q08188
Clone Names 80703052
Peptide ID 80703052
Additional Information
Gene ID 7053
Other Names Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG(E), TGE, TGase E, Transglutaminase-3, TGase-3, Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain, Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain, TGM3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TGM3
Function Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross- linking structural proteins to hardening the inner root sheath.
Research Areas
Citations (0)

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Transglutaminases are enzymes that catalyze thecrosslinking of proteins by epsilon-gamma glutamyl lysineisopeptide bonds. While the primary structure of transglutaminasesis not conserved, they all have the same amino acid sequence attheir active sites and their activity is calcium-dependent. Theprotein encoded by this gene consists of two polypeptide chainsactivated from a single precursor protein by proteolysis. Theencoded protein is involved the later stages of cell envelopeformation in the epidermis and hair follicle.


Yamane, A., et al. FEBS J. 277(17):3564-3574(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Negishi, A., et al. Cancer Sci. 100(9):1605-1611(2009)Fujimoto, A., et al. J. Hum. Genet. 54(8):461-465(2009)Uemura, N., et al. Int. J. Cancer 124(9):2106-2115(2009)

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$ 80.00
Cat# BP17540b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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