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ZBTB4 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9P1Z0
Clone Names 80703105
Peptide ID 80703105
Additional Information
Gene ID 57659
Other Names Zinc finger and BTB domain-containing protein 4, KAISO-like zinc finger protein 1, KAISO-L1, ZBTB4, KIAA1538
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB4
Synonyms KIAA1538
Function Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688).
Cellular Location Nucleus. Chromosome. Note=Localizes to chromocenters.
Research Areas
Citations (0)

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Background

ZBTB4 may be involved in transcriptional regulation.

References

Sasai, N., et al. Nucleic Acids Res. 38(15):5015-5022(2010)Yamada, D., et al. Oncogene 28(27):2535-2544(2009)Weber, A., et al. EMBO J. 27(11):1563-1574(2008)Filion, G.J., et al. Mol. Cell. Biol. 26(1):169-181(2006)

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$ 80.00
Cat# BP17542c
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