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ZBTB4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9P1Z0 |
|---|---|
| Clone Names | 80703105 |
| Gene ID | 57659 |
|---|---|
| Other Names | Zinc finger and BTB domain-containing protein 4, KAISO-like zinc finger protein 1, KAISO-L1, ZBTB4, KIAA1538 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZBTB4 |
|---|---|
| Synonyms | KIAA1538 |
| Function | Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self- renewal (By similarity). |
| Cellular Location | Nucleus. Chromosome. Note=Localizes to chromocenters |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ZBTB4 may be involved in transcriptional regulation.
References
Sasai, N., et al. Nucleic Acids Res. 38(15):5015-5022(2010)Yamada, D., et al. Oncogene 28(27):2535-2544(2009)Weber, A., et al. EMBO J. 27(11):1563-1574(2008)Filion, G.J., et al. Mol. Cell. Biol. 26(1):169-181(2006)
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