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DUSP6 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16828
Clone Names 100430231
Peptide ID 100430231
Additional Information
Gene ID 1848
Other Names Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3, DUSP6, MKP3, PYST1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUSP6
Synonyms MKP3, PYST1
Function Inactivates MAP kinases. Has a specificity for the ERK family.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the dualspecificity protein phosphatase subfamily. These phosphatasesinactivate their target kinases by dephosphorylating both thephosphoserine/threonine and phosphotyrosine residues. Theynegatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different membersof the family of dual specificity phosphatases show distinctsubstrate specificities for various MAP kinases, different tissuedistribution and subcellular localization, and different modes ofinducibility of their expression by extracellular stimuli. Thisgene product inactivates ERK2, is expressed in a variety of tissueswith the highest levels in heart and pancreas, and unlike mostother members of this family, is localized in the cytoplasm. Twotranscript variants encoding different isoforms have been found forthis gene.


Chiappinelli, K.B., et al. Gynecol. Oncol. 119(1):146-150(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Nunes-Xavier, C.E., et al. J. Biol. Chem. 285(34):26417-26430(2010)Zhang, Z., et al. Carcinogenesis 31(4):577-586(2010)Wang, Z., et al. Mol. Vis. 16, 1696-1704 (2010) :

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$ 80.00
Cat# BP17558a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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