|Other Names||Protein crumbs homolog 3, CRB3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions.|
|Cellular Location||Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells|
|Tissue Location||Preferentially expressed in epithelial tissues. Expressed at high levels in lung, kidney, retina, colon and mammary glands. Expressed at moderate levels in liver, spleen, pancreas, placenta and prostate.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Crumbs family ofproteins. This protein may play a role in epithelial cell polarityand is associated with tight junctions at the apical surface ofepithelial cells. Alternate transcriptional splice variants,encoding different isoforms, have been characterized. [provided byRefSeq].
Pardossi-Piquard, R., et al. Biochemistry 46(48):13704-13710(2007)Fan, S., et al. J. Cell Biol. 178(3):387-398(2007)Fogg, V.C., et al. J. Cell. Sci. 118 (PT 13), 2859-2869 (2005) :Lemmers, C., et al. Mol. Biol. Cell 15(3):1324-1333(2004)Roh, M.H., et al. J. Cell. Sci. 116 (PT 14), 2895-2906 (2003) :
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.