|Other Names||Homeobox protein Hox-C10, Homeobox protein Hox-3I, HOXC10, HOX3I|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.|
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This gene belongs to the homeobox family of genes. Thehomeobox genes encode a highly conserved family of transcriptionfactors that play an important role in morphogenesis in allmulticellular organisms. Mammals possess four similar homeobox geneclusters, HOXA, HOXB, HOXC and HOXD, which are located on differentchromosomes and consist of 9 to 11 genes arranged in tandem. Thisgene is one of several homeobox HOXC genes located in a cluster onchromosome 12. The protein level is controlled during celldifferentiation and proliferation, which may indicate this proteinhas a role in origin activation.
Hwang, J.H., et al. Cloning Stem Cells 11(2):269-279(2009)Zhai, Y., et al. Cancer Res. 67(21):10163-10172(2007)Gabellini, D., et al. EMBO J. 22(14):3715-3724(2003)Kosaki, K., et al. Teratology 65(2):50-62(2002)Sandrock, B., et al. J. Biol. Chem. 276(38):35328-35333(2001)
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