|Other Names||Zinc phosphodiesterase ELAC protein 1, Deleted in Ma29, ElaC homolog protein 1, Ribonuclease Z 1, RNase Z 1, tRNA 3 endonuclease 1, tRNase Z 1, ELAC1, D29|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.|
|Cellular Location||Cytoplasm, cytosol. Nucleus. Note=Mainly cytosolic|
|Tissue Location||Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas|
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Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Takahashi, M., et al. FEBS Lett. 582(17):2532-2536(2008)Takaku, H., et al. Nucleic Acids Res. 31(9):2272-2278(2003)Yanaihara, N., et al. Genomics 72(2):169-179(2001)Tavtigian, S.V., et al. Nat. Genet. 27(2):172-180(2001)
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