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ALS2CL Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q60I27 |
|---|---|
| Clone Names | 110726009 |
| Gene ID | 259173 |
|---|---|
| Other Names | ALS2 C-terminal-like protein, ALS2CL |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ALS2CL |
|---|---|
| Function | Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. |
| Cellular Location | Cytoplasm. Note=Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells |
| Tissue Location | Expressed in heart and kidney. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ALS2CL acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.
References
Suzuki-Utsunomiya, K., et al. Biochem. Biophys. Res. Commun. 354(2):491-497(2007)Hadano, S., et al. FEBS Lett. 575 (1-3), 64-70 (2004) :
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