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PPFIA2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O75334
Clone Names 110726163
Peptide ID 110726163
Additional Information
Gene ID 8499
Other Names Liprin-alpha-2, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2, PTPRF-interacting protein alpha-2, PPFIA2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Cellular Location Cytoplasm. Cell surface. Note=Colocalizes with PTPRF at the cell surface
Tissue Location Expressed only in brain.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the LARprotein-tyrosine phosphatase-interacting protein (liprin) family.Liprins interact with members of LAR family of transmembraneprotein tyrosine phosphatases, which are known to be important foraxon guidance and mammary gland development. It has been proposedthat liprins are multivalent proteins that form complex structuresand act as scaffolds for the recruitment and anchoring of LARfamily of tyrosine phosphatases. This protein is most closelyrelated to PPFIA1, a liprin family member known to interact withthe protein phosphatase LAR. The expression of this gene is foundto be downregulated by androgens in a prostate cancer cell line.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Ko, J., et al. J. Biol. Chem. 278(43):42377-42385(2003)Ko, J., et al. J. Neurosci. 23(5):1667-1677(2003)Fujinami, K., et al. Int. J. Mol. Med. 10(2):173-176(2002)Wyszynski, M., et al. Neuron 34(1):39-52(2002)

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$ 80.00
Cat# BP17576c
Availability: In Stock
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